Developed by Metabolic Pharmaceuticals as a candidate anti-obesity agent
Potential reduction in depression, cognitive decline, and dementia risk, particularly in older individuals
NNMT inhibitors are selective and do not impact related methyltransferases or enzymes in the NAD + salvage pathway The selectivity of NNMT inhibitors was confirmed by testing against a panel of structurally similar methyltransferases and two enzymes in the NAD + salvage pathway (NAMPT and SIRT1
Pancreatitis in cats The pancreas is an organ in the body located close to the stomach
Some people are more likely to run low, including: Vegans and vegetarians People with digestive issues (like IBS or coeliac) Older adults Anyone on certain medications People recovering from illness We dont guess
[1] For example, if a 2 mL dose (full 200 mg thiamine, 200 mg niacinamide) is to be given IV, a nurse might mix it into 50 mL of saline and infuse over 15-30 minutes